I still think we need to aquire the complete mosquito Genome, which would require some hunting given how we failed last time, in order to release a gaint cloud of mosquitoes to suck the blood of every living creature in range of the pond!
Given that our strength is clearly DNA modification, I see this as a very reasonable plan, since then we would have access to vast DNA libary with which to modify our minions and our self. With this libary, we could modify ourself to any situation, or have severl minions situited to each and every situation.
Also, once we start aquiring numerous species, the DNA libary should just be organized by species. That would be easier to navigate, and likley shorter. Similiar species can be eliminated, because similiar DNA would not matter given our modification abilities. We just need acess to a broad range of DNA, and once that is aquired, we can become anything we wish.
Also if you guys really want to kill zee humans, we could just use our spider DNA to manufacture deadly venom and develop fangs with which to inject the human with it. The venom really doesn't even need to be that deadly per ounce, most species try to conserve their venom, since it is expensive to produce, but since we have a lot of biomass, nutrients, and energy, we could just inject the human with copious amounts of venom.
Once the human is injected with the copious amounts of venom, he will quickly die. We can then pull him into the lake, and eat him there.