Depending on your skill levels, supplies, and background, you can always rig booby traps to fend off the police when they do searches at your safehouses (or when you raid other houses). Invest in a few bear traps, plant them near your windows and doorways, and you'll have fewer mobile forces (especially dogs). You can always have sulphuric acid (mad scientist SKer) to throw into their eyes as well, along with melting evidence.
Take down some cops, and you can stockpile tazers, pepper bombs/sprays, anti-riot claymores (the non-lethal kind; though you would more likely get those from SWAT teams), and further increase personal security. Pepper bombs and sprays will do wonders against dogs. You can also try to produce mustard gas bombs/traps by using a few household chemicals and cooking pots as well (good for deep indoor defense). Or make bombs/napalms or toxic traps using other household items. MacGuyver some deathtraps.
We can always go a Face/Off approach, kill (or knock out) a target, carry their corpse with you (keep it fresh; or carrying a cooler for the head will also suffice), go to a back alley doctor before the skin rots away too much, and do a face swap. Lay low for enough days/weeks (your face needs to heal), and you'll be back into society with a new face with lower recognizability (though a little disfigured each swap, depending on the doctor's skill, and how well you keep the healing process clean). You can also, provided high enough pain tolerance, scramble (requires a knife of sorts) or melt off your fingerprints to slow down tracking even further.