If you haven't, check out the
relevant wiki page for an in-depth breakdown that will let you roll up your own optimized builds.
For outrunning death squads, I would just select
A - the Polish priest Popieluszko was kidnapped by government agents. for the first question and
D - surviving alone, just like anyone. But we can't go on like this. for the last question. This gives +3 health and +4 agility, which should set you up fine for footchases. You'll also have first aid, which is great for not getting killed in the field.
If you're using cars, make sure to recruit a really good driver for the chases -- try recruiting a motorcyclist or truck driver, for example. And steal a sports car. Your founder can only start with 2 points of driving max, which isn't quite where you want to be for life and death situations, and the Beetle you can get for picking the answer about a car is probably slower than most pursuers.
My recommendation for both a pure seduction build and a pure persuasion/charisma build, in one founder, is:
E - the Sandanista Front won the elections in Nicaragua. (+2 CHA)
E - my father lectured me endlessly, trying to make me think like him. (+1 CHA, +1 Psychology)
E - I was the class clown. I even had some friends. (+1 CHA, +1 Persuasion)
D - my parents divorced. Mom slept with the divorce lawyer. (+1 Seduction)
B - I played guitar in a grunge band. We sucked, but so did life. (+2 CHA, +2 Music)
D - when I was sent to religious counseling, just stressing me out more. (+1 Religion, +1 Psychology)
E - I was resorting to controlling people. Had my own clique of outcasts. (+1 CHA, +2 Persuasion)
D - I let people pay me for sex. I needed the money to survive. (+1 CHA, +2 Seduction)
D - I went to party and met a cool law student. We've been dating ever since. (Start with a Lawyer recruited as a sleeper love slave.)
E - writing my manifesto and refining my image. I'm ready to lead. (+2 CHA, +2 INT, +1 Writing, +1 Law, +2 Persuasion, +50 Juice, $50, Industrial Tenement Safe House)
You can have very minor variations to prefer one or the other build, but this threads the needle and does both with little loss. This will have you set up with 12 charisma, 4 persuasion, and 3 seduction. You can pick the "homosexuality" choice instead of "controlling people" if you want +1 seduction in exchange for less charisma and persuasion. you can also change the question that starts you with a law student sleeper if you don't want to use up a seduction "slot" on a lawyer sleeper, though lawyer sleepers are amazing, so I still suggest keeping it.
My personal playing style involves a mix of combat and stealth, so I would pick a lot of A and B choices, trying to optimize agility, strength, and health. I'd make sure to pick up both stealth and security along the way, and I'd dip into E for the "swords" questions, since swords are really cool in LCS.