OK, I already gave my opinion on the game in my old video game review topic, but here is a good a place as any to give my (less-than) professional option on Dead Space.
The plot (as you know) features the titular engineer (or: not a Spess Mahreen) Isaac Clarke, who is sent to the unresponsive Ishimura with the supportive cast and red shirts to fix a communication array. The shit hits the fan very early in the game and starts a series of unfortunate events as you run back and forth between the Nostromo, amassing more gibs and spare limbs than a Vietnam movie set. The plot itself is a bit cliche (but what isn't nowadays?) but it makes it up with setting and creepiness. the problem is that, after the first few chapters, it becomes harder and harder to keep that scariness when you'd have enough ammo and health packs to last you the whole game and the first weapon is the only one you really need (although I can't advise against getting the ripper), even on impossible I found it a little too easy.
I honestly found the controls just fine, since it's already been run through another classic Resident Evil 4. I actually applaud with what they did with the HUD, allowing to get all of the details of the Ishimura. Graphics were...you know what, screw the graphics, if I cared one spittle about graphics, I'd just throw away my Xbox and watch Event Horizon over and over. The scare chord is one of the more overused cliches in horror games, but I could have sworn that it play when there was no monsters in the room, so I looked it up and apparently the scare chords aren't scripted event, which I guess is pretty cool it there weren't played so often. I've said it before that horrors now longer try any deep suspense and instead are packed with attempts to simply startle the viewer/player. I'll at least give Dead space a B- for effort, as atmosphere is rather creepy (although I've seen enough boltgun gray and flickering lights to last me a lifetime, so it loses some pinch) and there are some actually horrifying parts (being chased by the regenerator), but by the end it become less survival horror and more adventure shooter with really ugly monsters.
Overall, I give Dead Space a thumbs up, but unless your the %100 completion type a person I'd advise renting before actually buying. The lack of replay value puts a blow to the game, but there's a lot in the game to actually look over. So while you may only play the game twice at most there's still plenty to find. As for predictions for the squeal, I admit I'm really gitty over what's to come.