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[Kyubee]

The idea is basically, that when a dwarf is born (perhaps with a higher chance if born in an evil biome), they have a chance (I'd say like, 1% normally, but when in an evil biome, anywhere from 10% to 90%, depending on the level of biome evil) to be born with one or more deformities. Said deformities could be helpful (an extra pair of arms, stronger or even metallic bones, demigod-like stat bonuses), harmful (constant pain, weaker bones, horrendous stats, permanent cave adaptation), or just odd (Two right hands, two left feet, a skull outside the skin, odd pigmentations).

Perhaps these could also be developed by continuous drinking of evil water, and perhaps syndromes could deliver such changes, both procedural and deliberate.

Would definitely make dwarven super soldier projects more fun than just throwing them into pools of vampire blood after a childhood in Dwarven Daycare.

Perhaps such mutations could even have their own raws, so one can add their own.

[Azerty]

Genetics should have to play, along with toxics.

[George_Chickens]

Yeah, this could be cool, but I personally would rather wait until we have a more fleshed out genetics system. If it's just "random chance for cancer" it's not really all that fun to deal with.

[Pillbo]

You might be interested in this thread
http://www.bay12forums.com/smf/index.php?topic=173189.0

Deformity is one of the magical spheres in the game so should show up as an effective force when the magic arc comes out

DEFORMITY

Spoiler (click to show/hide)

Spell effects:

• Spells that cause deformity (duh), tumors, growths, "elephant man" type physical effects- bones bending, mouths or eyes growing over with flesh or bone
• Spells that cause deformity in plants.
• Spells that cause out of control growth in plants.
• Spells that rob someone of their beauty.
• Spells that turn beautiful objects into ugly objects, or objects that are difficult to look at/cause disturbance.
• Cursed items that make people repulsive or become deformed

Environmental effects:

• From LOW-HIGH levels:  Increasingly misshapen landscapes, broken mountains. Maybe canyons or mountains that don't make sense, as in not formed by water runoff in logical ways. I don't have much specific for this, but anything can be deformed. Increasingly negative mood effects on creatures
• At MEDIUM levels:  All natural beauty is gone. The environment makes creatures feel physically repulsed/disgusted. Elves couldn't be here, goblins would maybe like it?...
• At HIGH levels:Mountains that get wider as they increases in elevation like globes. Rains toxic and deformed vermin. Stone & soil in the earth becoming increasingly crude oil, uranium, plutonium, mercury, basically anything horrible.
• At EXTREME levels: Rivers of mercury, lakes or oil and tar, everything is radioactive, soils are coal dust, aquifers of oil, rains oil, tumors, gore

Creature effects:

• At LOW levels: Unusual effects on newborns and long term residents, hair all falling out, eyes or teeth enlarging, bulbous features
• At MEDIUM levels: Everyone/thing is ugly/unsightly. Children born with missing or extra body parts. Conjoined twins/triplets/ect. Some creatures don't ever stop growing their whole lives
• At HIGH levels: Extremely hazardous to creatures, tumors grow wildly on just about anything, Civs will no longer consider animals edible out of disgust. Creatures born with mismatched (for their species) body parts (dwarfs with squid tentacles, puppies with turtle shells, elves with beards).  Marriage, romance, pregnancy all become almost unthinkable in this environment, insanity high.
• At EXTREME levels: Every living things is horribly mis-formed and barely able to live at best. creatures like floating guts, demons, elementals, blobs, jellys and about all that can live here.  Creatures are lumpy and tumor-like losing most of their original shape. Creatures continuously melt/grow into/split off of each other in a Cronenbergian hellscape. Literally hell on earth?

Plant effects:

• At LOW levels: misshapen fruits/seeds
• At MEDIUM levels: bulbous plants, trees growing wider and shorter
• At HIGH levels: All beauty is gone, civs will no longer consider plants edible out of disgust. trees growing along the ground in snaking strange ways, with large wide then skinny sections, fruit growing from trunks of trees/wrong parts of plants. Trees grown fast and entomb objects like swords, armor and corpses left in a field after battle.
• At EXTREME levels: trees growing trunks like a starfish in any direction up, down or to the sides; some huge bulbous trunks with virtually no vertical growth, trees growing upside down, fruit and leaves growing from roots, roots growing up into the sky. Some trees no wood, just bark growing tumor-like from the ground. Trees replacing the ground like a shell, a thick, solid, woody groundcover

Item effects:

• At LOW-HIGH levels: Items increasingly lose functionality to deformity
• At HIGH levels:  Items become unsightly and repulsive, function is greatly reduced.
• At EXTREME levels: Items become nonfunctional from deformity.

Feel free to add any suggestions.

[GoblinCookie]

The idea is basically, that when a dwarf is born (perhaps with a higher chance if born in an evil biome), they have a chance (I'd say like, 1% normally, but when in an evil biome, anywhere from 10% to 90%, depending on the level of biome evil) to be born with one or more deformities. Said deformities could be helpful (an extra pair of arms, stronger or even metallic bones, demigod-like stat bonuses), harmful (constant pain, weaker bones, horrendous stats, permanent cave adaptation), or just odd (Two right hands, two left feet, a skull outside the skin, odd pigmentations).

It really should be a region aligned to deformity not evil, *if* regions aligned to evil are even in at that point. 

In addition to the effect from location, there should be a rather small random chance for all dwarves to get deformities, a chance increased by their level of inbreeding.  We could probably create a random list of specific deformities that are particularly likely to occur in a particular creature. 

Also bad mutations/deformities should be far more common than good ones.