Well, there's Nightvale. Wait. Shit.
Ok let's try this again. I've got a few suggestions to make! Limetown was interesting shortie, but goodie I listened to a while back. It's incredibly well-produced and they are moving on within that story soon, with a new update coming up this year I think? If you enjoy gaming podcasts even a little bit, you might find Cthulhu and Friends interesting. It follows a group of players as they play Call of Cthulhu. The GM does a killer job and ends up blending Sci-fi into the world in a way that works.
In the vein of Sci-Fi, SAYER is incredible and has a strong Space Station 13 vibe as you follow workers throughout their day with the titular AI, SAYER. As the show goes on, the plot gets thicker and they are now in their 5th season I think? Regardless, I recommend it a LOT for existential horror and mad, but productive science.
Last but not least, I'm going to give a sideways shout out to Drunks and Dragons. They are a part of the community that produced Sayer and Cthulhu and Friends as well. Basically, drunk people get together and start to play DnD. It's recommended that you start in places other than the very first episodes, since that is also them just learning how to play the game, but they've got some good moments and are a pretty damn fun group to listen to. Episode 32 is a good place to start from what I understand, or at the beginning of a season. It can be a bit of a slog sometimes, but hey, if you want a helluva lot of listening material look no further.